levofloxacin 500 mg dosage

Due to high rates of resistance, fluoroquinolones are not recommended for treatment of gonococcal infections in the US; use of this drug should be considered if infection is most likely due to enteric organisms and tests have ruled out gonorrhea. Each drug prolongs the QTc interval, which may increased the risk of Torsade de pointes, other serious arryhthmias, and sudden death. Joint, muscle, or tendon pain, swelling, or stiffness. Levofloxacin 500 MG Tablet fights against bacterial infections like tuberculosis, pneumonia, laryngitis, cellulitis, gastroenteritis, acute or chronic bronchitis, urinary tract infections, tonsillitis, anthrax and plague. Comments: US CDC Recommendations: 500 mg orally once a day for 7 days This drug should be used only if the potential benefit justifies the potential risk. Drug administration should begin as soon as possible after suspected/confirmed exposure to aerosolized Bacillus anthracis. adagrasib, levofloxacin. levofloxacin and pasireotide both increase QTc interval. This damage may be permanent. Minor (1)levofloxacin increases levels of flurazepam by decreasing metabolism. Drug administration should begin as soon as possible after suspected/confirmed exposure to Yersinia pestis. levofloxacin and lumefantrine both increase QTc interval. Use Caution/Monitor. Efficacy studies not conducted in humans with plague for ethical and feasibility reasons; approval based on efficacy study in animals. Minor/Significance Unknown. Separate by 2 hours. hydroxychloroquine sulfate and levofloxacin both increase QTc interval. This drug can also cause tremors, agitation, anxiety, confusion, delirium, and hallucinations. Comment: Risk of CNS stimulation/seizure. There are also case reports of quinolones increasing phenytoin levels. other information we have about you. Use Caution/Monitor. Current guidelines should be consulted for additional information. Serious - Use Alternative (1)sevoflurane and levofloxacin both increase QTc interval. ceritinib and levofloxacin both increase QTc interval. 2.1 Dosage of Levofloxacin Tablets in Adult Patients with Creatinine Clearance > 50mL/minute The usual dose of Levofloxacin Tablets is 250 mg, 500 mg, or 750 mg administered orally every 24 hours, as indicated by infection and described in Table 1. Use Caution/Monitor. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. Monitor Closely (1)levofloxacin increases effects of rosiglitazone by pharmacodynamic synergism. Avoid or minimize exposure to natural or artificial sunlight; use sun protection (e.g., protective clothing, sunscreen) if sun exposure cannot be avoided. Administer the injection only by IV infusion; not for IM, intrathecal, intraperitoneal, or subcutaneous administration. Other (see comment). Exercise extreme caution when vilanterol coadministered with drugs that prolong QTc interval; adrenergic agonist effects on the cardiovascular system may be potentiated. Applies only to oral forms of hormone. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Monitor Closely (1)triclabendazole and levofloxacin both increase QTc interval. Follow your doctor's orders or the directions on the label. Other (see comment). levofloxacin, tolfenamic acid. ECGs should be obtained for high risk patients. ECG monitoring is recommended, along with drugs that may prolong the QT interval. Monitor Closely (1)triptorelin increases toxicity of levofloxacin by QTc interval. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Minor (1)levofloxacin will decrease the level or effect of biotin by altering intestinal flora. ozanimod and levofloxacin both increase QTc interval. Theyll ultimately prescribe the smallest dosage that provides the desired effect. levofloxacin increases toxicity of aminolevulinic acid topical by pharmacodynamic synergism. Infections/Infestations: Culture and susceptibility (periodically during therapy). . information is beneficial, we may combine your email and website usage information with Avoid or Use Alternate Drug. Mechanism: Displacement of GABA from receptors in brain. Healthline Media does not provide medical advice, diagnosis, or treatment. Modify Therapy/Monitor Closely. Slight and transient QT-prolongation observed with ezogabine, particularly when dose titrated to 1200 mg/day. In this article, learn about Enterococcus faecalis infections, including their symptoms, transmission, and how to prevent them. Other (see comment). Learn about different types and treatments of urinary tract infections, the risk factors, and prevention for both men and women. These recommendations apply to patients with creatinine clearance 50 mL/minute. Available for Android and iOS devices. ketoconazole and levofloxacin both increase QTc interval. Monitor Closely (1)lithium and levofloxacin both increase QTc interval. Levofloxacin 500 MG Infusion is fluoroquinolone antibiotic used for the treatment of bacterial infections affecting the lungs, skin and urinary tract - the kidneys, bladder, ureters, or urethra. Quinolone antibiotic administration may result in hyper- or hypoglycemia. Other (see comment). Applies only to oral form of both agents. Stop this drug and contact healthcare provider if tendon pain, swelling, or inflammation develops or you have weakness or are unable to use 1 of your joints; rest and do not exercise. Call your doctor if your infection doesnt get better within a week of finishing this drug. Monitor Closely (1)promazine and levofloxacin both increase QTc interval. levofloxacin decreases effects of phenytoin by unknown mechanism. Comment: Risk of CNS stimulation/seizure. polysaccharide iron decreases levels of levofloxacin by inhibition of GI absorption. Levofloxacin caused no impairment of fertility or reproductive performance in rats at oral doses as high as 360 mg/kg/day, corresponding to 4.2 times the highest recommended human dose based upon relative body surface area and intravenous doses as high as 100 mg/kg/day, corresponding to 1.2 times the highest recommended human dose based upon . inotuzumab and levofloxacin both increase QTc interval. Use Caution/Monitor. Tendon damage, including tendinitis (inflammation of the tendon) and tendon rupture (tear in the tendon). Serious - Use Alternative (1)levofloxacin, vandetanib. When flying, never put it into a checked bag. Monitor Closely (1)imipramine and levofloxacin both increase QTc interval. Serious - Use Alternative (1)ceritinib and levofloxacin both increase QTc interval. Administer oral levofloxacin 2 hr before or after administration of polyvalent cation containing products. Tell your doctor right away if you get sunburned or have skin blisters/redness.Levofloxacin may cause live bacterial vaccines (such as typhoid vaccine) to not work well. This can cause your body to process drugs more slowly. This drug is indicated for the treatment of adults with mild, moderate, and severe infections due to susceptible isolates of the designated bacteria. Either increases toxicity of the other by QTc interval. Minor (1)levofloxacin will decrease the level or effect of pyridoxine (Antidote) by altering intestinal flora. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Avoid or Use Alternate Drug. Review/update the Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. [3] Drugs that prolong the QTc interval and may potentiate the effects of beta2 agonists on the cardiovascular system; increased risk of ventricular arrhythmias. It also comes in an intravenous (IV) form thats only given by a healthcare provider. Complete antibiotic regimens 2-4 days before initiating microbiota oral. This medicine is best taken with a full glass (8 ounces) of water. fluvoxamine and levofloxacin both increase QTc interval. Talk with your doctor if you have a history of aortic aneurysm. May administer the tablets without regard to meals; administer the oral solution 1 hour before or 2 hours after eating. Do not keep outdated medicine or medicine no longer needed. All rights reserved. maprotiline and levofloxacin both increase QTc interval. Your doctor may need to change your antibiotic. Monitor Closely (1)levofloxacin increases effects of repaglinide by pharmacodynamic synergism. Take at least 2 hours before and not less than 6 hours after administration of sodium picosulfate, magnesium oxide and anhydrous citric acid to avoid magnesium chelation. By clicking send, you acknowledge that you have permission to email the recipient with this information. Avoid or Use Alternate Drug. If you have low blood sugar levels while taking this drug, stop taking it and call your doctor right away. Applies only to oral forms of hormone. Levofloxacin may interact with other medications. Use Caution/Monitor. Monitor Closely (1)valbenazine and levofloxacin both increase QTc interval. epinephrine and levofloxacin both increase QTc interval. Use Caution/Monitor. erythromycin stearate and levofloxacin both increase QTc interval. Your risk is greater if you have a history of depression. magnesium supplement will decrease the level or effect of levofloxacin by Other (see comment). Avoid or Use Alternate Drug. Oral Solution: Store at 25C (77F); excursions permitted to 15C to 30C (59F to 86F). Monitor Closely (1)levofloxacin increases effects of vildagliptin by pharmacodynamic synergism. Serious - Use Alternative (1)arsenic trioxide and levofloxacin both increase QTc interval. These drugs are often used to treat similar conditions. Avoid or Use Alternate Drug. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Either decreases levels of the other by inhibition of GI absorption. Increased pressure around the brainsevere headache, blurry vision, change in vision, nausea, vomiting. levofloxacin increases levels of midazolam by decreasing metabolism. levofloxacin will increase the level or effect of digoxin by altering intestinal flora. This raises your risk of side effects. Panobinostat is known to significantly prolong QT interval. Comment: Risk of CNS stimulation/seizure. vemurafenib and levofloxacin both increase QTc interval. Use Caution/Monitor. Monitor Closely (1)calcium carbonate, levofloxacin. Use Caution/Monitor. If interruption not possible, patients requiring therapy with a drug that prolongs QT should be closely monitored. More frequently reported side effects include: diarrhea and insomnia. promethazine and levofloxacin both increase QTc interval. Tremor Hyperglycemia (elevated blood glucose) Serious side effects of levofloxacin In a 2016 safety review, the FDA found that systemic (throughout the body) fluoroquinolone use is associated with uncommon, but potentially permanent and disabling adverse effects in the tendons, muscles, joints, nerves, and central nervous system (CNS). Monitor Closely (1)levofloxacin, meclofenamate. Applies only to oral forms of hormone. macimorelin and levofloxacin both increase QTc interval. Drugs & Vitamins . Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. This drug may make your muscle weakness worse if you have myasthenia gravis. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. Serious - Use Alternative (1)buprenorphine subdermal implant and levofloxacin both increase QTc interval. Applies only to oral form of both agents. Other (see comment). Avoid or Use Alternate Drug. Administer oral levofloxacin 2 hr before or after administration of polyvalent cation containing products. Use Caution/Monitor. Talk with your doctor about other drug options that may work for you. Applies only to oral form of both agents. ribociclib increases toxicity of levofloxacin by QTc interval. Avoid or Use Alternate Drug. Increases risk of torsades de pointes. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Last updated on Dec 22, 2022. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Use Caution/Monitor. amoxapine and levofloxacin both increase QTc interval. Use Caution/Monitor. Other (see comment). Modify Therapy/Monitor Closely. Low risk of contraceptive failure. Monitor Closely (1)sertraline and levofloxacin both increase QTc interval. Minor (1)levofloxacin increases levels of quazepam by decreasing metabolism. Monitor Closely (1)ferric citrate will decrease the level or effect of levofloxacin by drug binding in GI tract. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Levofloxacin can cause mild or serious side effects. Mechanism: unknown. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. There havent been enough studies done involving humans to be certain how the drug might affect the fetus. Dont store this medication in moist or damp areas, such as bathrooms. prochlorperazine and levofloxacin both increase QTc interval. Slight and transient QT-prolongation observed with ezogabine, particularly when dose titrated to 1200 mg/day. Other (see comment). Quinolone antibiotic administration may result in hyper- or hypoglycemia. levofloxacin decreases effects of BCG vaccine live by pharmacodynamic antagonism. sorafenib and levofloxacin both increase QTc interval. sodium picosulfate/magnesium oxide/anhydrous citric acid decreases levels of levofloxacin by cation binding in GI tract. Use Caution/Monitor. Use Caution/Monitor. HOW TO USE: Read the Medication Guide provided by your pharmacist before you start using levofloxacin and each time you get a refill. hydrocortisone rectal and levofloxacin both increase Other (see comment). Most Modify Therapy/Monitor Closely. To help keep the amount constant, do not miss any doses. Either increases effects of the other by QTc interval. Monitor Closely (1)levofloxacin increases effects of insulin aspart by pharmacodynamic synergism. Call your doctor right away if you have serious side effects. Use Caution/Monitor. levofloxacin increases toxicity of umeclidinium bromide/vilanterol inhaled by QTc interval. Comment: Risk of CNS stimulation/seizure. Comment: Risk of CNS stimulation/seizure. Use Caution/Monitor. Use Caution/Monitor. Infections can range from mild to severe. That means two things: Talk to your doctor if youre pregnant or planning to become pregnant. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. desflurane and levofloxacin both increase QTc interval. levofloxacin and venlafaxine both increase QTc interval. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Modify Therapy/Monitor Closely. Low risk of contraceptive failure. Do not use medications containing ofloxacin while using levofloxacin.This medication may interfere with certain lab tests (such as urine screening for opiates), possibly causing false test results. Other (see comment). Therapy may be started before test results are known; appropriate therapy should be continued when results are available. Avoid or Use Alternate Drug. Other (see comment). Monitor Closely (1)desipramine and levofloxacin both increase QTc interval. Use Caution/Monitor. Heart rhythm problems, such as prolongation of the QT interval. levofloxacin, tretinoin. levofloxacin, sulindac. Mechanism: Displacement of GABA from receptors in brain. levofloxacin increases levels of temazepam by decreasing metabolism. levofloxacin will decrease the level or effect of thiamine by altering intestinal flora. Use Caution/Monitor. Serious - Use Alternative (1)ibutilide and levofloxacin both increase QTc interval. pharmacodynamic antagonism. Mechanism: Displacement of GABA from receptors in brain. This can help keep levels of this drug from building up too much in your body. Monitor Closely (1)levofloxacin increases effects of glimepiride by pharmacodynamic synergism. This can cause your body to process drugs more slowly. Modify Therapy/Monitor Closely. Applies only to oral forms of hormone. Use Caution/Monitor. Comment: Risk of CNS stimulation/seizure. Modify Therapy/Monitor Closely. Minor (1)levofloxacin, isotretinoin. levofloxacin increases levels of lormetazepam by decreasing metabolism. Levofloxacin oral tablet is used for short-term treatment. selpercatinib increases toxicity of levofloxacin by QTc interval. Either decreases levels of the other by inhibition of GI absorption. SIDE EFFECTS: See also Warning section.Pain/redness/swelling at the injection site, nausea, diarrhea, headache, dizziness, lightheadedness, or trouble sleeping may occur. Serious - Use Alternative (1)selinexor, levofloxacin. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. Use Caution/Monitor. Advertising revenue supports our not-for-profit mission. Other (see comment). University of Illinois-Chicago, Drug Information Group. When dosage in patients with CrCl at least 50 mL/min is 750 mg every 24 hours: 750 mg orally or IV once, followed by 500 mg orally or IV every 48 hours, When dosage in patients with CrCl at least 50 mL/min is 500 mg every 24 hours: 500 mg orally or IV once, followed by 250 mg orally or IV every 48 hours, When dosage in patients with CrCl at least 50 mL/min is 250 mg every 24 hours: Data not available, Hemodialysis: 750 to 1000 mg orally or IV 3 times a week. ECG should be monitored closely. Use Caution/Monitor. To view formulary information first create a list of plans. Minor/Significance Unknown. Either decreases levels of the other by inhibition of GI absorption. Alcohol consumption may reduce the effectiveness of certain antibiotics, but according to a 2020 review, moderate alcohol consumption does not seem to have an adverse effect on Levofloxacin. QTc interval. rose hips decreases levels of levofloxacin by inhibition of GI absorption. sucralfate decreases levels of levofloxacin by inhibition of GI absorption. Use Caution/Monitor. Levofloxacin works by killing the bacteria that are causing an infection. Use Caution/Monitor. Applies only to oral forms of hormone. Take at least 2 hours before and not less than 6 hours after administration of sodium picosulfate, magnesium oxide and anhydrous citric acid to avoid magnesium chelation. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Levofloxacin is used to treat a variety of bacterial infections. Serious - Use Alternative (1)levofloxacin and pimozide both increase QTc interval. Use Caution/Monitor. Mechanism: Displacement of GABA from receptors in brain. valbenazine and levofloxacin both increase QTc interval. Monitor Closely (1)erythromycin base and levofloxacin both increase QTc interval. levofloxacin increases effects of chlorpropamide by pharmacodynamic synergism. Use Caution/Monitor. ECG should be monitored closely. Minor/Significance Unknown. Levofloxacin Dosage Medically reviewed by Drugs.com. This can lead to severe bleeding and death. The absolute bioavailability of a 500 mg tablet and a 750 mg tablet of levofloxacin are both approximately 99%, demonstrating complete oral absorption of levofloxacin. Applies only to oral form of both agents. Monitor Closely (1)chloroquine increases toxicity of levofloxacin by QTc interval. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Fact versus fiction: A review of the evidence behind alcohol and antibiotic interactions. Bioterrorism-related cases: To complete an antimicrobial regimen of up to 60 days from onset of illness. Use Caution/Monitor. If we combine this information with your protected Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor/Significance Unknown. A prescription for this medication is refillable. fluphenazine and levofloxacin both increase QTc interval. Minor/Significance Unknown. Do not put this medication in your cars glove compartment or leave it in the car. Avoid coadministration of QTc prolonging drugs with ivosidenib or replace with alternate therapies. Store this drug at 68F to 77F (20C to 25C). trazodone and levofloxacin both increase QTc interval. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. levofloxacin increases effects of metformin by pharmacodynamic synergism. Monitor Closely (1)thioridazine and levofloxacin both increase QTc interval. These infections include: Levofloxacin may be used as part of a combination therapy. Serious - Use Alternative (1)encorafenib and levofloxacin both increase QTc interval. Contraindicated (1)levofloxacin will increase the level or effect of fezolinetant by affecting hepatic enzyme CYP1A2 metabolism. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. 2023 Healthline Media LLC. Monitor Closely (1)dronedarone and levofloxacin both increase QTc interval. Use Caution/Monitor. Minor/Significance Unknown. Taking it again could be fatal (cause death). information highlighted below and resubmit the form. thioridazine and levofloxacin both increase QTc interval. QT interval should be monitored when ezogabine is prescribed with agents known to increase QT interval. This increases your risk of side effects. Try to remove any weapons, medications, or other potentially harmful objects. This drug has boxed warnings. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Use Caution/Monitor. Always carry the original prescription-labeled box with you. Monitor Closely (1)epinephrine and levofloxacin both increase QTc interval. This content does not have an Arabic version. arsenic trioxide and levofloxacin both increase QTc interval. Minor/Significance Unknown. Use Caution/Monitor. Modify Therapy/Monitor Closely. If parenteral cephalosporin therapy is not possible, use of this drug (with oral metronidazole) can be considered if community prevalence and individual risk for gonorrhea are low. Levofloxacin can cause a severe allergic reaction, even after only one dose. levofloxacin and ofloxacin both increase QTc interval. Also tell them about any vitamins, herbs, and supplements you use. However, the dose is usually not more than 250 mg. $109.76 medication_outlined Availability Available See GoodRx coupons What is Levofloxacin? Separate by 2 hours. Oral Acute bacterial sinusitis Adult: 500 mg once daily for 10-14 days. Safety of this drug has not been established for therapy durations exceeding 28 days; prolonged therapy recommended only when the benefit outweighs the risk. Low risk of contraceptive failure. Coadministration of quinolone antibiotics and corticosteroids may increase risk of tendon rupture. Quinolone antibiotic administration may result in hyper- or hypoglycemia. levofloxacin will decrease the level or effect of conjugated estrogens by altering intestinal flora. The side effects of . perphenazine and levofloxacin both increase QTc interval. Use Caution/Monitor. If concomitant use is required it's recommended that toremifene be interrupted. Levofloxacin 500 MG Infusion is a medicine that is a member of the fluoroquinolone antibiotic family. Other (see comment). Use Caution/Monitor. Other (see comment). Comment: Risk of CNS stimulation/seizure. Comment: Risk of CNS stimulation/seizure. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Other (see comment). Use Caution/Monitor. Comment: Risk of CNS stimulation/seizure. Serious - Use Alternative (1)ferrous sulfate decreases levels of levofloxacin by inhibition of GI absorption. Systemic anthrax includes anthrax meningitis, inhalation anthrax, injection anthrax, gastrointestinal anthrax, and cutaneous anthrax with systemic involvement, extensive edema, or lesions of the head or neck. Your doctor will determine the best dosage to suit your needs. The potential additive effects on heart rate, treatment with ozanimod should generally not be initiated in patients who are concurrently treated with QT prolonging drugs with known arrhythmogenic properties. You should not drive, use machinery, or do other tasks that require alertness or coordination until you know how it affects you. . A class of drugs is a group of medications that work in a similar way. It is also used to treat anthrax infection after inhalational exposure. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Symptoms can include: yellowing of your skin and whites of your eyes. (2020). General symptoms include chest pain, fever, cough, and trouble breathing. levofloxacin and pazopanib both increase QTc interval. Use Caution/Monitor. Mechanism: Displacement of GABA from receptors in brain. The WHO recommends susceptibility testing and a tailored regimen using second-line drugs based on test results, if testing and second-line drugs are available. Avoid or Use Alternate Drug. Minor/Significance Unknown. Avoid or Use Alternate Drug. If you are a Mayo Clinic patient, this could Monitor Closely (1)levofloxacin and moxifloxacin both increase QTc interval. Other (see comment). Minor (1)levofloxacin, aceclofenac. Avoid or Use Alternate Drug. other information we have about you. Either increases effects of the other by QTc interval. This increases your risk of side effects. Levofloxacin is also used to treat and prevent plague (including pneumonic and septicemic plague). Comment: Risk of CNS stimulation/seizure. Drug administration should begin as soon as possible after suspected/confirmed exposure to aerosolized B anthracis. Monitor Closely (1)levofloxacin will decrease the level or effect of estrogens conjugated synthetic by altering intestinal flora. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. This drug hasnt been studied in children younger than 6 months. To provide you with the most relevant and helpful information, and understand which Last updated on Jul 6, 2022. Use Caution/Monitor. Monitor Closely (1)levofloxacin increases effects of tolazamide by pharmacodynamic synergism. Avoid coadministration of cholera vaccine with systemic antibiotics since these agents may be active against the vaccine strain. Other (see comment). Applies only to oral form of both agents. Monitor Closely (1)levofloxacin increases effects of metformin by pharmacodynamic synergism. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Minor (1)levofloxacin increases levels of clonazepam by decreasing metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely. asenapine and levofloxacin both increase QTc interval. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. eliglustat and levofloxacin both increase QTc interval. Use Caution/Monitor. Last medically reviewed on September 20, 2021. Use Caution/Monitor. Mechanism: Displacement of GABA from receptors in brain. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Be sure to avoid doing this when the weather is very hot or very cold. ECG monitoring is recommended, along with drugs that may prolong the QT interval. As a result, more of a drug stays in your body for a longer time. Monitor Closely (1)buprenorphine transdermal and levofloxacin both increase QTc interval.

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